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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e0b94641c4e822d96cfc1ac603641b52c8ec779a49a0d9fca1eb585fcbaf1a' 
  AND token = 'LX39CVh2HuYQeewePeHD1WXkmeaw5vZxuJ7QFkU8E6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}