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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38027e7365ce13329ba998bcc5404d191d4169c46c5563d1797f5e510cd3ccff' 
  AND token = 'mlDVmAfJoe8Qx6bF/rDYGKEZ1u3sXMAYdTYQhBX8+Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}