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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ef8160817bcd6612a8b133b56fafe7d9e3c8a47f68558138c9deb04caeb62c' 
  AND token = 'OhkShSf3GBkMTo6q8PkmhLerDyx7MCeejs4fNlEZUvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}