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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f185733d4dd3694aa8bde48d44dcd5e78e256743906641c5089212d104213a' 
  AND token = 'Z3IhQD+rYxASFeea67s40+ibSMf9JkG035+2SLaVVf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}