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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8c2f14383eaca930fea31c459291f0f1a024449add974a1cf7f81ed7ecbe68' 
  AND token = '6kzXin13oTUCZ8qY/EHOEGXHByF+HWnnZ2ifM20MPbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}