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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec50bdebf37222e41abb170cdfc9c279b37200f7db0f577a16fab4437e925f61' 
  AND token = '1W/t8dHogeWrCtEdnAHfFT7JwQ6fPT9nYKvsLSkw3UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}