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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce314bd86df7bbca9cdbf7067f11f8daa7bf1fc26adced8730293a8c53e536d4' 
  AND token = 'qDFaHulqZ1MrDbPXBwoqkcUjHIqrUgpPz0ObQ00XxSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}