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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fb07ff3b4bcf8e014a8516a3faba18f63524130cddc29df34bf195243e29af' 
  AND token = 'MRxBtql5JjJjLAbLl7615dFeoSvy+qryS09+lv1Kmbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}