SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e1ae67a8555879fdeb27f8ad7032c1ed12d52509aa3f36e27de17ae3e33543' 
  AND token = 'r7U3LlHAwT4BnlLkjD0tzcRLtyuxlq+66vSMMenK9XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}