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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29856c0fb1f7f518abaa29ea008f52501883d28c8c0df2d8bb922db4bccbaeab' 
  AND token = 'enV4ARllIh9ixtkGV+dF68lVbJ0l4xVRwvh4mVG5790=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}