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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7963d603b4570c09fe2d459a2f9ae96dc043078d8c6d960f33b8d3ae1bc4b45' 
  AND token = 'taJSeGEgzIsk/T2B9EJrF7NeaOfnPgVe83Hp/5Nk3pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}