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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe3c1be02363b7b7442469ed5ce2a727d80320ae9d523f68e5f9f74f29d9f7a' 
  AND token = '3DnCmsCgIWCaGsiNLjcX0mtL9CMsW+TfTUtUAT683QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}