SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c5f9c06fe59bd496d12d33fa64f9750f2f317307272ff37f80e35ced7b7958' 
  AND token = 'H8EXZFGHF+aCcPgSGPd1xUz9TLzHmgYiRvFReElvcuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}