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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd74f069d52aafed1f62f7e8cb307174462c6b8174ab022495bce07d763c65e7' 
  AND token = 'lQDJDekFe1Vk3O7x+2v4n0eRGBqnghby5u7JSuEvUTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}