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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2180c8565e09f0096ae0dd9241e330f411c6ddb57cab3830e65bea92cc11742c' 
  AND token = 'oZqFX9Ql6S9ZOFegUr+YK+S4rklY/DFozNSQ4fMpseI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}