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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35827c4804a8643a9baa2d281d6b9d70191f86eb59062af78a1f6f03a75961d6' 
  AND token = 'PPrxPXfJm3TUaQzb0nt3hV4CAPF9Vn48XFDxN+ZllQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}