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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bf94af887f47c70a65ea604f4b41fbf541d284dcb743493c752649c5320347' 
  AND token = 'Nya+iOCz/PPv3KVp//e8/xg/FS65RQ9P/v5LWwmWanM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}