SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f7c6134744b5c4853e0ec7e88f81aef81e52b7323a8c60f729a462974285c4' 
  AND token = '4UNKabP3WhFT/iSKnMsHQ1kQJipGD3kYUXaCIWtbxAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}