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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a0229635dfb38183a17c4646b20b7d010b0a6de3196cde1ed99a617da82b5de' 
  AND token = '1LpG+gE6ib0GuPNdL+vypSonuauGo5GqPzRcXVm698k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}