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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810555bc51bfc854a93496ba41da4b3e881140000a3102873504e89e91cb661c' 
  AND token = 'uvIqJK9zt31wb3et11DX/IEP92LM5JC6xaFTtND4zuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}