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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0800eea485728144eda395367970f685200ec1aa8108583d30a1c2d527883e18' 
  AND token = 'giWdwwwueFrIpfK/g5k7YhiRLJ+NueNUZm6QpXKm5TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}