SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2552adb25755c83fdfa9ba5e05f88aa8194232e5dff5ded8dc8f0e22407c8642' 
  AND token = 'PTOFSMU/wknCvSsoTiQdbe2yw0N87DAcvUWEZ14dDyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}