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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37f485cd3f6b0cde4ca7470b195f33fa6fb1b9ee03180d569d2198aa78616d5' 
  AND token = 'qnqkNoY+K1Wo7LNguzeFeyCmPDwXwDe1bRiAnAaSiEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}