SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7b443b7362caf6c9125d1a811f2b8f61bafdeea8c21498b5c647e4cd6051068' 
  AND token = '/ySNUyMsDR5Cv5Klth0s5lacpT+N7nXBZ1y1q+HN5Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}