SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb6d988e999acb7c305ca7abf9bd43fd6f43df34b328cc7924b6c33f69204b0' 
  AND token = 'Qye+wonaSH8ppzmp2Fa8DHDFbSGywC5mRtpy9PZwOxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}