SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e2e057b9029b0bde71f7e17d797e368d3ab6f049a0bae4123c52c4259c9616' 
  AND token = 'SBiVSib8s2s+rsj/c/HllG702YC3EcJHAvHzkfU3Z+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}