SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b401b0068208b3c1ac90e8cb822a1716a4bfe273e2e66d86b75d49c7904ac8' 
  AND token = 'hF1KkLXec4DIsqu5fEkksfCz+Dz5O91lpqRhdyCxP6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}