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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48342fea3d61d4e2766c4b7ac39eed5b613d93e897ff844a426ac0e1f8c23f0f' 
  AND token = 'rf6by6w6uLvnyeU+qBLPz1Lxpp8mu3DqRK6OUkrfXNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}