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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdea5914458189622f44a928ed05df171a636a9345a83a58a02aea3f9e4113e4' 
  AND token = 'yvSXv8gEQK/TazMVuL9MpcFeV+18y3xUKYxg4VEHnRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}