SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afceb6ca10d290e5351f274987c757cbe1c5ff4f30d934c1200242b4b7f48ffb' 
  AND token = 'DA21eBLcXH+rcu8H05P3UrOEzi6cPcGZdTZfFkvZHCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}