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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca23ce6cb64fd7a0c46bfd298c49edbfacf77a022f8a4979972daad1a7775ed' 
  AND token = 'VAuk5VbSMZWt82OhKLX8wTKeJvdxj+QjWB0UNCjtR5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}