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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dddebb44c59e262ff57c75e5f6ab140d32b279c58dc53deb258eca11b4ce75' 
  AND token = '40vLN8b9XREgiLe241aPQgcs1mH97c7T4w2EMWqPqA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}