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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605f0ece05cc55600366446fde8534a1706acefdc510cdf298f3db6dc8b2dcf2' 
  AND token = 'U/3U+5RFVLAGGO4Hy1pOgFmPo1BqjQbpGq6QWf1rs4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}