SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ecdae985c7acc63bd4a2240aa668c9a44af25659b674cc39c7aebdd8c7fb46' 
  AND token = 'VweXFXf4xDEdaM9f0qIt1v/BUI/SXGvzWWBlaNpwpwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}