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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a581d860a9087af06ef126a157fa7090f33de91b5245a3e52c3671ea7f63e702' 
  AND token = 'Jk4LZ7L+tB5jzaN0fwMtUJH3/YJrHJTK4jZSyNKFgL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}