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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e517ffc758cec9bae39f5c39ee27c8aca73e4a9dca204661d7c338b5a3aec80a' 
  AND token = '65mi7RFypm2gUXA22lW1Qg/zmLLnKkSGaoPyMSb2tco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}