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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff87608a7972fd2241899c143be920abe91f05432379e28b4d480de58c28a6bf' 
  AND token = 'VYRbOPXyOo+kmEeCtMdIqWthZkf/Y9gae+EAnRHR2Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}