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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fb224d6cf815f4e5c4cd5c455811e74201d84d2d57b6e66e9a6466aeef37de1' 
  AND token = 'Dem+vWaFjb5QVGn2p5Hp96lf9cRJI5qpY3i9x89fKpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}