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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2d1be7a316e61a6725d1d7878a846a0453e25d624bda2889da1bde01074e33' 
  AND token = 'ssCcbRI2kCWFAW5ilq89QSCXkNeUy5P4/fKST/eqeMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}