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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04152aa67831b45e6b937dae2f52c0dc95b801820d632937ed1c1ae127f0978c' 
  AND token = 'ua4TnbfxE4Q24F1WXB1b+T4wBH3UOSAQU27mpUFxKHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}