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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de78d1be6e92a416d4d5b1a332020190cb2ca783022ce31f73fb7d6e471327f9' 
  AND token = 'ffNTGUDqbWF8kZARtooTBUI2WlAekm5y6Xmqnai3nuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}