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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37863d7462d79ad9d5ea0875ee9f11cca36a28e6ac246ac951d0781a4c1653fb' 
  AND token = 'cQOyP7cNn0KvKRS2McI9qGz3C1GvolrRdZEKACF5rlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}