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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d63587dc00d544a351443306d7785e1323757ba6b2df03308447983e5e567e4' 
  AND token = 'DAOTYMjU5vg6ymxmnVbJ6hxallRSKZELAZcA0zMZsTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}