SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50cf87e694ca0ed27b0843888c6eb51b41e7e3eeea6c65d11e269b6896e42d51' 
  AND token = '03G3Vs2OYIOMvsm72XV1A1dS5nR1sCT0/7vpKRz737E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}