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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243b7ba41964d94dd01b05da2d1e6ad82441ff1fad1820d046937fb201ab3ebc' 
  AND token = 'BMICaf8f2DQ+QmmVGUWoMcQennHFDpfTxiUsn6Av37Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}