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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6520621a0c68d91a97aaf6bd8f196753043048ab21432fe7fd0f100c9deedf01' 
  AND token = 'B6p1cUk5MwPYzep35G55dAvOqSrI/iD2xk+VSkD4etU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}