SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cb422d5aed5cb2ec4c73950c9ec326db4acbefbc7bfd2670c706646852d341' 
  AND token = 'ggZnNT8LhKHSEygXnBaKYptq3KfwpXedOPp01krfBZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}