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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b08a58f2ce5337e433b0f16a84be59063cf1cc6d3f536d6d1281d091af2ad18d' 
  AND token = 'fMAzjyG0DGjxKw62/7UsA5fxRDGrNybr29pcL90hgA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}