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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b971fa5e9ba8af52da2807fff8418cb1ad3ee261e49a7be1c7353476171b66' 
  AND token = 'VE2WWKGNMyuoR5VKVaBQaeOcd8j+b8FNbeNdhxedleY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}