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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '897ac64831b29c1543af4433c2197b785d9b0476477d8050f692866e9b613725' 
  AND token = 'W6Y2v1ciBytaHLj+cQROL2PpLxM/7kr9gBylEEMuuEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}